diluting heparin for flushes |
Q. You have run out of pre mixed vials of heparin flush and
are going to need to make some. Standard heparin flushes for pediatric units is 10 units per 1 cc and is used on all peripheral IV's. You have a 50 cc bag of .9 NS and Heparin 1000 units/ 10 cc. How many cc's of heparin would you need to add to your 50 ml bag?
Now normally I would call the pharmacy.. but this is the only one that I cannot figure out on my own. I
don't do proportions so I need a way of doing it without the cross multiplications. SO....... is
there a calculator on your site that maybe I am just not pulling the info out of the question to fill the calculator?? Or is
this unrealistic to hope that I can get away without proportions?
A. This is the best solution I could come up for your problem. You want to use a 1000 unit vial of heparin to make a 10:1 heparin flush mixture. Using the following formula,
dose
available |
x desired volume of concentration |
Using your example:
1000 units = dose available
10 units = desired dose of concentration
1 mL = desired volume of concentration
1000
u |
x 1 mL | = 100 mL |
The answer is 100 mL. 100 milliliters of dilutant are needed to dilute 1000 units of heparin into a 10 unit/1 mL mixture. Make sure and mark this bag with all the necessary information including total dosage and total volume.
NOTE: Since the 1000 units of heparin was in a 10 mL vial you will have to account for this volume. Withdraw 10 mL of your dilutant (i.e. normal saline) and waste it otherwise you will have a total volume of 110 mL.
Try the calculator below to solve the example.